Using temperature to awaken immune response to fight brain cancer

14 Oct 2019 Cancer

This certainly may apply to many cancers, as unfortunately, most are immunologically “cold,” which is why the current FDA approved immunotherapies fail in the majority of cases. There are numerous techniques to turn “cold” tumors to “hot.” Among these are injection into a tumor TLR agonist, STING agonist, CD40 agonist, and Oncopore peptides, to name a few. This article discusses using ultrasound to control temperature. The surprising aspect was it was not necessarily heating things up, like hyperthermia, but keeping the temperature stable. A very interesting and unexpected conclusion.

There is also a nice animation explaining the immune response to cancer and how cancer can evade the immune system.

Source: Labroots

Photo: Pixabay

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