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TitleDescription Author
Creatine powers fight against cancer, improves efficacy of immunotherapiesCreatine is a popular organic acid that is widely used as a supplement by bodybuilders and athletes. A new study has found that creatine is a potent molecular battery that powers the immune cells to better fight cancer. Angela Betsaida B. Laguipo, BSN
Image Guided CryoablationImage Guided Cryoablation of Cancer with Intra-Tumor Injection of anti-CTLA-4 and PD-1 Immune Checkpoint Inhibitors. Alternative Treatments for CancerJason R. Williams MD, Patrick E. Sewell MD, Mark A. Rosenberg MD
CpG Cryo DendriticIn vivo Colocalization of Antigen and CpG within Dendritic Cells Is Associated with the Efficacy of Cancer Immunotherapy.Stefan Nierkens, Martijn H. den Brok, Roger P.M. Sutmuller, Oliver M. Grauer, Erik Bennink, Mary E. Morgan, Carl G. Figdor, Theo J.M. Ruers, and Gosse J. Adema
DIPP4T Cell TraffickingDipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy.Rosa Barreira da Silva, Melissa E. Laird, Nader Yatim, Laurence Fiette, Molly A. Ingersoll & Matthew L. Albert
Local CTLA4 InjectionControlled Local Delivery of CTLA-4 Blocking Antibody Induces CD8þ T-Cell–Dependent Tumor Eradication and Decreases Risk of Toxic Side Effects Marieke F. Fransen, Tetje C. van der Sluis, Ferry Ossendorp, Ramon Arens, and Cornelis J.M. Melief
Off-Label PropanololOff-Label Propanolol Reduces Melanoma Recurrence Vincenzo De Giorgi, MD; Marta Grazzini, MD; Silvia Benemei, MD; et al
Immuno-Thermal AblationsImmuno-thermal ablations – boosting the anticancer immune response Ryan Slovak, Johannes M. Ludwig, Scott N. Gettinger, Roy S. Herbst and Hyun S. Kim
Ablation MechanismsThermal ablation of tumors; biological mechanisms and advances in therapy. Katrina F. Chu and Damian E. Dupuy
Ablation VaccineSaponin-based adjuvants create a highly effective anti-tumor vaccine when combined with in situ tumor destruction. Martijn H. den Brok, Stefan Nierkens, Jori A. Wagenaars, Theo J. Ruers, Carla C. Schrier, Eric O. Rijke, Gosse J. Adema
Intratumoral CTLA4Intratumoral Anti-CTLA-4 Therapy: Enhancing Efficacy While Avoiding Toxicity. Martijn H. den Brok, Stefan Nierkens, Jori A. Wagenaars, Theo J. Ruers, Carla C. Schrier, Eric O. Rijke, Gosse J. Adema
Low Dose CyclophosphimideCyclophosphamide Unmasks an Antimetastatic Effect of Local Tumor Cryoablation. Moshe Yair Levy, Abhinav Sidana, Wasim H. Chowdhury, Steven B. Solomon, Charles G. Drake, Ronald Rodriguez, and Ephraim J. Fuchs
Intratumoral ImmunizationIntratumoral Immunization: A New Paradigm for Cancer Therapy Aurélien Marabelle, Holbrook Kohrt, Christophe Caux, et al.
Eradication Of Spontaneous Malignancy By Local ImmunotherapyHuman trials are set to commence after a potential cancer vaccine was shown to eliminate all traces of tumors in mice. Idit Sagiv-Barfi, Debra K. Czerwinski, Shoshana Levy, Israt S. Alam, Aaron T. Mayer, Sanjiv S. Gambhir and Ronald Levy