| Title | Description | Author |
|---|---|---|
| Creatine powers fight against cancer, improves efficacy of immunotherapies | Creatine is a popular organic acid that is widely used as a supplement by bodybuilders and athletes. A new study has found that creatine is a potent molecular battery that powers the immune cells to better fight cancer. | Angela Betsaida B. Laguipo, BSN |
| Image Guided Cryoablation | Image Guided Cryoablation of Cancer with Intra-Tumor Injection of anti-CTLA-4 and PD-1 Immune Checkpoint Inhibitors. Alternative Treatments for Cancer | Jason R. Williams MD, Patrick E. Sewell MD, Mark A. Rosenberg MD |
| CpG Cryo Dendritic | In vivo Colocalization of Antigen and CpG within Dendritic Cells Is Associated with the Efficacy of Cancer Immunotherapy. | Stefan Nierkens, Martijn H. den Brok, Roger P.M. Sutmuller, Oliver M. Grauer, Erik Bennink, Mary E. Morgan, Carl G. Figdor, Theo J.M. Ruers, and Gosse J. Adema |
| DIPP4T Cell Trafficking | Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy. | Rosa Barreira da Silva, Melissa E. Laird, Nader Yatim, Laurence Fiette, Molly A. Ingersoll & Matthew L. Albert |
| Local CTLA4 Injection | Controlled Local Delivery of CTLA-4 Blocking Antibody Induces CD8þ T-Cell–Dependent Tumor Eradication and Decreases Risk of Toxic Side Effects | Marieke F. Fransen, Tetje C. van der Sluis, Ferry Ossendorp, Ramon Arens, and Cornelis J.M. Melief |
| Off-Label Propanolol | Off-Label Propanolol Reduces Melanoma Recurrence | Vincenzo De Giorgi, MD; Marta Grazzini, MD; Silvia Benemei, MD; et al |
| Immuno-Thermal Ablations | Immuno-thermal ablations – boosting the anticancer immune response | Ryan Slovak, Johannes M. Ludwig, Scott N. Gettinger, Roy S. Herbst and Hyun S. Kim |
| Ablation Mechanisms | Thermal ablation of tumors; biological mechanisms and advances in therapy. | Katrina F. Chu and Damian E. Dupuy |
| Ablation Vaccine | Saponin-based adjuvants create a highly effective anti-tumor vaccine when combined with in situ tumor destruction. | Martijn H. den Brok, Stefan Nierkens, Jori A. Wagenaars, Theo J. Ruers, Carla C. Schrier, Eric O. Rijke, Gosse J. Adema |
| Intratumoral CTLA4 | Intratumoral Anti-CTLA-4 Therapy: Enhancing Efficacy While Avoiding Toxicity. | Martijn H. den Brok, Stefan Nierkens, Jori A. Wagenaars, Theo J. Ruers, Carla C. Schrier, Eric O. Rijke, Gosse J. Adema |
| Low Dose Cyclophosphimide | Cyclophosphamide Unmasks an Antimetastatic Effect of Local Tumor Cryoablation. | Moshe Yair Levy, Abhinav Sidana, Wasim H. Chowdhury, Steven B. Solomon, Charles G. Drake, Ronald Rodriguez, and Ephraim J. Fuchs |
| Intratumoral Immunization | Intratumoral Immunization: A New Paradigm for Cancer Therapy | Aurélien Marabelle, Holbrook Kohrt, Christophe Caux, et al. |
| Eradication Of Spontaneous Malignancy By Local Immunotherapy | Human trials are set to commence after a potential cancer vaccine was shown to eliminate all traces of tumors in mice. | Idit Sagiv-Barfi, Debra K. Czerwinski, Shoshana Levy, Israt S. Alam, Aaron T. Mayer, Sanjiv S. Gambhir and Ronald Levy |
