Does Black Pepper enhance the Curcumin effect?

We had previously discussed Curcumin properties that included anti-inflammatory, antioxidant, and anti-carcinogenic by acting on cell proliferation, cell survival, death receptors, and tumor suppression pathways. However, ingesting curcumin alone does not lead to the associated health benefits due to its poor bioavailability, which appears to be due to poor absorption, rapid metabolism, and rapid elimination; curcumin doesn’t absorb into the bloodstream easily and therefore relies on methods to increase bioavailability. This is where consuming it with black pepper is important.

Black pepper’s active ingredient, piperine, is responsible for black pepper’s rich flavor and helps inhibit drug metabolism; piperine helps increase the rate at which curcumin is absorbed by the body and its bioavailability in the body; for example, the liver is in charge of getting rid of substances by making them water-soluble so they can be excreted, and piperine acts on this effect so curcumin is not excreted as fast, and its effects can be enhanced; it has been shown that piperine can increase curcumin bioavailability by 2000%, so all of the health effects of curcumin as antioxidant, anti-inflammatory, anti-carcinogenic, the effect on metabolic syndrome and arthritis are enhanced and, therefore, your overall health.

Reference: Prasad, S. (9 de June de 2014). Does black pepper enhance the curcumin effect? Journal of Traditional and Complementary Medicine, 140-146. doi:10.4103/2225-4110.130992

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