Williams Cancer Institute

COFFEE AND COLORECTAL CANCER: NEW INSIGHTS

COFFEE AND COLORECTAL CANCER: NEW INSIGHTS


Recent research from the Netherlands made by Oyelere et al suggests that coffee drinkers, particularly those with colorectal cancer, may have a lower risk of cancer recurrence and improved survival rates. In a study of 1,719 individuals, it was found that patients who consumed at least two cups of coffee per day had a reduced likelihood of cancer relapse in the future. The study also indicated a correlation between coffee intake and decreased mortality rates among colorectal cancer patients, especially in earlier stages of the disease.

Interestingly, the benefits of coffee consumption appeared to peak at three to five cups per day, with the greatest reduction in all-cause mortality observed in this range. However, consuming more than five cups daily did not provide further benefits and may even have adverse effects on health.

While the exact mechanisms behind these findings are not fully understood, hypotheses suggest that coffee’s antioxidant properties or its impact on gut microbiota and metabolic pathways could play a role in reducing cancer recurrence and improving overall health outcomes.

Although more research is needed to establish a causal relationship between coffee consumption and cancer outcomes, these findings provide valuable insights for future intervention studies and the development of guidelines for colorectal cancer patients. The study emphasizes the importance of further investigating the potential therapeutic effects of coffee in cancer treatment and management.

Published in the International Journal of Cancer, this study contributes to our understanding of the relationship between coffee consumption and cancer recurrence rates, highlighting the need for continued research in this area.

Reference: Abisola M. Oyelere, Dieuwertje E. Kok, Daniel Bos, Marc J. Gunter, Pietro Ferrari, Pekka Keski-Rahkonen, Johannes H. W. de Wilt, Henk K. van Halteren, Ewout A. Kouwenhoven, Fränzel J. B. van Duijnhoven, Ellen Kampman, 12 February 2024, Coffee consumption is associated with a reduced risk of colorectal cancer recurrence and all-cause mortality, https://doi.org/10.1002/ijc.34879 

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