immune system

Many may be wondering how exactly the immune system and cancer are interrelated. It’s quite complex given that it has taken decades of countless scientific research in search of the cure. The goal is to break this cancer into its basic mechanisms to fully understand its totality and appreciate its processes. In general, the immune system works by fighting against any harmful substances such as bacteria, fungi, viruses, and cancer cells. Something important to note is that your own cells and immune system can and will betray you.

Immunotherapy for Cancer

Immune response in cancer treatments has been studied for over decades and to this day continues to be closely researched in an attempt to provide a less invasive treatment for patients. Thanks to medical research, patients and physicians have access to seventeen immunotherapy FDA approved treatments. This ongoing mission is one of great value and in today’s blog we will be exploring more interesting details about the immune system and cancer.

Arthritis Drugs for Cancer Immunotherapy

The immune system produces proteins, known as chemokines, which are signals that can affect immune function. There is a chemokine named C-C motif ligand 20, also known as CCL20. It is known as an inflammatory protein, often associated with rheumatoid arthritis. However, new evidence links this cytokine with numerous cancers. It seems that CCL20 promotes cancer metastasis. In addition, it increases cancer stem cells and causes T cell exhaustion. These actions will suppress an immune response. There are studies in many cancer types indicating that blocking CCL20 is anti-cancer and may enhance the success of immunotherapy. Surprisingly enough, drugs that can block CCL20 may also reduce autoimmune side-effects from standard PD-1 immunotherapy, such as Opdivo and Keytruda.

Optimizing Immune system

Many may be wondering how exactly the immune system and cancer are interrelated. It’s quite complex given that it has taken decades of countless scientific research in search of the cure. The goal is to break this cancer into its basic mechanisms to fully understand its totality and appreciate its processes. In general, the immune system works by fighting against any harmful substances such as bacteria, fungi, viruses, and cancer cells. Something important to note is that your own cells and immune system can and will betray you.