Williams Cancer Institute

COFFEE AND COLORECTAL CANCER: NEW INSIGHTS

COFFEE AND COLORECTAL CANCER: NEW INSIGHTS Recent research from the Netherlands made by Oyelere et al suggests that coffee drinkers, particularly those with colorectal cancer, may have a lower risk of cancer recurrence and improved survival rates. In a study of 1,719 individuals, it was found that patients who consumed at least two cups of […]

BOOSTING BREAST CANCER RADIOTHERAPY WITH VALPROIC ACID ANALOGUES

BOOSTING BREAST CANCER RADIOTHERAPY WITH VALPROIC ACID ANALOGUES Breast cancer is one of the most common diseases among women, and its treatment poses a significant medical challenge. Radiotherapy has long been a cornerstone in the battle against this type of cancer, as it not only directly targets cancer cells but can also trigger an immune […]

THE ROLE OF VALPROIC ACID IN OVERCOMING TUMOR RESISTANCE

THE ROLE OF VALPROIC ACID IN OVERCOMING TUMOR RESISTANCE   In recent decades, immune checkpoint blockade therapy has shown great promise in treating multiple types of cancer by strengthening the body’s immune response. However, many patients do not respond well to this therapy, possibly due to the presence of immunosuppressive cells in the tumor microenvironment. […]

EMEND (APREPITANT) FOR NAUSEA ALSO BE ANTI-CANCER

EMEND (APREPITANT) FOR NAUSEA ALSO BE ANTI-CANCER It has been discussed how the use of dexamethasone for nausea related to chemo needs to be reconsidered since it may negatively affect the response, especially when immunotherapy is involved. Emend, generic name aprepitant is also an option for chemo induced nausea. Unlike dexamethasone, it may be anti-cancer. […]

CHRONIC STRESS AND CANCER SPREAD: UNRAVELING THE SCIENTIFIC INSIGHTS

CHRONIC STRESS AND CANCER SPREAD: UNRAVELING THE SCIENTIFIC INSIGHTS In a recent study conducted with mice, researchers may have uncovered a potential link explaining how chronic stress can contribute to the spread of cancer. Scientists from Cold Springs Harbor Laboratory in New York discovered evidence suggesting that stress could induce changes in specific immune cells, […]

MICROBIAL CLUES: A POTENTIAL BREAKTHROUGH IN COLORECTAL CANCER DIAGNOSIS

MICROBIAL CLUES: A POTENTIAL BREAKTHROUGH IN COLORECTAL CANCER DIAGNOSIS Colorectal cancer, traditionally associated with individuals over 50, is increasingly affecting younger populations without the benefit of routine screening. A recent study, published in eBioMedicine, delves into the gut microbiome, specifically exploring microbial differences in colorectal cancer patients of varying age groups. This exploration could hold […]

GUT MICROBIOTA, BACTERIAL STRAINS, AND IMMUNOTHERAPY IN CANCER TREATMENT

GUT MICROBIOTA, BACTERIAL STRAINS, AND IMMUNOTHERAPY IN CANCER TREATMENT Recent advancements in cancer treatment have seen the emergence of immune checkpoint blockade (ICB) therapy, revolutionizing the field by leveraging the immune system’s capabilities. Despite its success in certain cancers, variability in response rates and primary resistance have spurred investigations into the role of the gut […]

UNLOCKING THE IMMUNE SYMPHONY: GUT MICROBIOME’S ROLE IN CANCER THERAPY

UNLOCKING THE IMMUNE SYMPHONY: GUT MICROBIOME’S ROLE IN CANCER THERAPY Cancer, recognized as a global public health challenge, has spurred extensive research to combat its growing social and economic burden. The intricate mechanisms governing tumor development, progression, and metastasis have been unveiled through decades of research, exposing the complex interplay between the host’s immune status […]

FMT AND PANCREATIC CANCER: UNVEILING NEW PATHS FOR IMMUNOTHERAPY

FMT AND PANCREATIC CANCER: UNVEILING NEW PATHS FOR IMMUNOTHERAPY In a groundbreaking clinical trial, researchers led by Dr. Florencia McAllister of the MD Anderson Cancer Center are embarking on an innovative exploration to assess the impact of fecal microbial transplants (FMT) on the unique tumor microbiome of patients with pancreatic ductal adenocarcinoma (PDAC). This trial, […]

THE ROLE OF TUMOR MICROBIOME DIVERSITY IN PANCREATIC CANCER SURVIVAL

THE ROLE OF TUMOR MICROBIOME DIVERSITY IN PANCREATIC CANCER SURVIVAL Pancreatic ductal adenocarcinoma (PDAC) is a highly fatal disease with limited treatment options. Long-term survival in PDAC is uncommon, and factors influencing it are not well understood. While the genomic landscape is often linked to survival, recent research suggests the importance of the tumor microbiome […]