Studies have shown that using image guided Cryoablation, a technique where a needle is placed into a tumor, then frozen, can enhance an anti-cancer immune response even in distant tumors. Further studies indicate that using this technique, combined with the injection of immunotherapy agents into the ablation and tumor site, can significantly enhance the effectiveness of the immune response, far more than just the medications or Cryoablation alone.
Your Advanced Cancer Treatment Procedures
New, precision approaches to cancer treatment that target and attack the tumor directly.
Immunotherapy agents such as the immune checkpoint inhibitors Opdivo, Keytruda, Yervoy and OX40 agonist have been a revolution in cancer treatment, but they still have significant limitations. Studies have shown that injecting these agents directly into a tumor may allow for more combinations, better success and less side effects than the typical intravenous administration. It is important to understand that this treatment is systemic, meaning it affects other tumors that are not directly injected. This means that it is not necessary to inject every tumor in cases where patients may have many. Also, patients already receiving intravenous immunotherapy may benefit by adding intratumoral immunotherapy to enhance their treatment. In addition, new experimental agents, such as an OX40 agonist, combined with CpG (called the Stanford cancer vaccine) have created even more excitement. This combination injected into the tumor, made worldwide news in early 2018, showing outstanding success with the idea of treating directly at a tumor site. The studies indicate that treating one or two sites can result in a whole body anti-cancer immune response. The idea is that training the immune system at the site where it actually encounters the cancer is the most important, not just all throughout the body. These trained immune cells can then attack cancer in locations throughout the body.
Cryoablation combined with Injection of Immunotherapy
Intravenous Immunotherapy combined with Intratumoral Injection of Immunotherapy
Breast Cancer Cryoablation
The future of breast cancer treatment, a minimally invasive procedure that can be essentially “scarless.” In addition, techniques such as vaccine adjuvants can be used to enhance the anti-cancer immune response of the Cryoablation procedure. We use techniques to minimize the spread and recurrence of cancer, such as the injection of NSAIDS (Ketorolac) directly into the tumor site when we perform ablations or biopsies.
What is Cryoablation?
Cryoablation is the placement of a needle into the tumor, freezing the tissue to destroy it. Typically this is for limited disease, but when combined with immunotherapy it can be helpful even in advanced cancers. This is because Cryoablation releases dead pieces of tumor that can be detected by the immune system, combined with immunotherapy; this functions like a cancer vaccine. See the video below for an explanation.
Lung Cancer Cryoablation
Delivers larger amounts of medication to the tumor with a lower dosage to you.
A less-invasive advantage for treating breast cancer.
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2919 E Commercial Blvd
Fort Lauderdale, FL 33308